Effect of rotenoids from the seeds of Millettia dura on larvae of Aedes aegypti.

@article{Yenesew2003EffectOR,
  title={Effect of rotenoids from the seeds of Millettia dura on larvae of Aedes aegypti.},
  author={Abiy Yenesew and Solomon Derese and Jacob Ogweno Midiwo and Matthias Heydenreich and Martin G. Peter},
  journal={Pest management science},
  year={2003},
  volume={59 10},
  pages={1159-61}
}
A crude chloroform extract of seeds of Millettia dura Dunn (Leguminosae) showed high activity (LC50 = 3.5 microg ml(-1) at 24 h) against second-instar larvae of the mosquito, Aedes aegypti L (Diptera: Culicidae). The rotenoids, deguelin and tephrosin, isolated from the seeds of this plant also showed potent activities, with LC50 values of 1.6 and 1.4 microg ml(-1) at 24 h, respectively. The related rotenoids millettone and millettosin were inactive at 20 microg ml(-1). Saturation at the B/C… CONTINUE READING
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