Effect of rotavirus vaccination on death from childhood diarrhea in Mexico.
@article{Richardson2010EffectOR, title={Effect of rotavirus vaccination on death from childhood diarrhea in Mexico.}, author={Vesta L Richardson and Joselito Hernandez-Pichardo and Manjari Quintanar-Solares and Marcelino Esparza-Aguilar and Brian M Johnson and C{\'e}sar Misael G{\'o}mez-Altamirano and Umesh D. Parashar and Manish M Patel}, journal={The New England journal of medicine}, year={2010}, volume={362 4}, pages={ 299-305 } }
BACKGROUND
A phased introduction of a monovalent rotavirus vaccine occurred in Mexico from February 2006 through May 2007. We assessed the effect of vaccination on deaths from diarrhea in Mexican children in 2008 and 2009.
METHODS
We obtained data on deaths from diarrhea, regardless of cause, from January 2003 through May 2009 in Mexican children under 5 years of age. We compared diarrhea-related mortality in 2008 and during the 2008 and 2009 rotavirus seasons with the mortality at baseline…
347 Citations
Effect of Rotavirus Vaccine on Diarrhea Mortality in Different Socioeconomic Regions of Mexico
- MedicinePediatrics
- 2013
After introduction of rotavirus vaccination, marked and sustained declines in diarrhea deaths were seen among children in all regions of Mexico, including in the least developed southern region with the highest baseline diarrhea mortality.
Impact of rotavirus vaccination on childhood deaths from diarrhea in Brazil.
- Medicine, Political ScienceInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
- 2011
Sustained Reduction of Childhood Diarrhea-Related Mortality and Hospitalizations in Mexico After Rotavirus Vaccine Universalization.
- Medicine, Political ScienceClinical infectious diseases : an official publication of the Infectious Diseases Society of America
- 2016
A substantial and sustained decline in diarrhea-related hospitalizations and deaths in Mexican children associated with implementation of rotavirus vaccination is documented, highlighting the public health benefits that could result in countries that adopt rotav virus vaccination into their national immunization programs.
Impact of Rotavirus Vaccination on Hospitalizations and Deaths From Childhood Gastroenteritis in Botswana.
- MedicineClinical infectious diseases : an official publication of the Infectious Diseases Society of America
- 2016
Following introduction of RV1 into the national immunization program, significant declines in hospitalizations and deaths from gastroenteritis were observed among children in Botswana, suggestive of the beneficial public health impact of rotavirus vaccination.
Baseline Estimates of Diarrhea-associated Mortality Among United States Children Before Rotavirus Vaccine Introduction
- MedicineThe Pediatric infectious disease journal
- 2011
Diarrhea-associated mortality among young US children from 1992 to 2006 is examined to establish baseline estimates through which the effect of rotavirus vaccines, introduced in 2006, can be assessed, and appears to be increasing in recent years.
Impact of rotavirus vaccination on childhood gastroenteritis-related mortality and hospital discharges in Panama.
- Medicine, Political ScienceInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
- 2012
Impact of Rotavirus Vaccine on Childhood Diarrheal Hospitalization After Introduction Into the South African Public Immunization Program
- MedicineThe Pediatric infectious disease journal
- 2013
At least 13,000 to 20,000 hospitalizations in children <2 years were prevented in the 2 years after rotavirus vaccine introduction, according to published estimates of rotav virus hospitalization burden.
Impact of rotavirus vaccination on rotavirus and all-cause gastroenteritis in peri-urban Kenyan children.
- MedicineVaccine
- 2017
Diarrhoea-related hospitalizations in children before and after implementation of monovalent rotavirus vaccination in Mexico.
- Medicine, Political ScienceBulletin of the World Health Organization
- 2014
Monovalent RVA vaccination has substantially reduced childhood diarrhoea-related hospitalizations for four continuous years in discretely different socioeconomic populations across Mexico.
Temporal Association of Rotavirus Vaccine Introduction and Reduction in All-Cause Childhood Diarrheal Hospitalizations in South Africa.
- MedicineClinical infectious diseases : an official publication of the Infectious Diseases Society of America
- 2016
An accelerated and sustained decline in all-cause diarrheal hospitalizations, temporally associated with rotavirus vaccine introduction, was observed in children <2 years of age, and the impact of other interventions such as improved sanitation and changes in HIV management cannot be discounted.
References
SHOWING 1-10 OF 16 REFERENCES
Diarrhea Morbidity and Mortality in Mexican Children: Impact of Rotavirus Disease
- MedicineThe Pediatric infectious disease journal
- 2004
A significant reduction in morbidity and mortality of severe diarrhea has occurred from 1990 and 2002 in Mexican children younger than 5 years old, a consequence of preventive programs initiated for cholera control since 1991, which had greater impact on SSS diarrhea and limited response for FWS diarrhea, when rotavirus is mainly present.
Global mortality associated with rotavirus disease among children in 2004.
- MedicineThe Journal of infectious diseases
- 2009
The high mortality associated with rotavirus disease underscores the need for targeted interventions, such as vaccines, to realize the full life-saving potential of vaccines.
Decline and Change in Seasonality of US Rotavirus Activity After the Introduction of Rotavirus Vaccine
- MedicinePediatrics
- 2009
The 2007–2008 US rotavirus season seems substantially delayed, shorter, and diminished in magnitude compared with seasons before vaccine implementation, suggesting indirect benefits to unvaccinated individuals.
Association between pentavalent rotavirus vaccine and severe rotavirus diarrhea among children in Nicaragua.
- MedicineJAMA
- 2009
Vaccination with RV5 was associated with a lower risk of severe rotavirus diarrhea in children younger than 2 years in Nicaragua but to a lesser extent than that seen in clinical trials in industrialized countries.
Seasonal diarrhoeal mortality among Mexican children.
- MedicineBulletin of the World Health Organization
- 1999
During the winter, there was a significant increase in the number of deaths that occurred in medical care units and among children who had been seen by a physician before they died, but deaths occurring at home showed no seasonal variation.
Efficacy of human rotavirus vaccine against rotavirus gastroenteritis during the first 2 years of life in European infants: randomised, double-blind controlled study
- MedicineThe Lancet
- 2007
Safety and efficacy of an attenuated vaccine against severe rotavirus gastroenteritis.
- MedicineThe New England journal of medicine
- 2006
Two oral doses of the live attenuated G1P[8] HRV vaccine were highly efficacious in protecting infants against severe rotavirus gastroenteritis, significantly reduced the rate of severe gastroenteropathy from any cause, and were not associated with an increased risk of intussusception.