Effect of risedronate on bone in renal transplant recipients.

  title={Effect of risedronate on bone in renal transplant recipients.},
  author={Maria Coco and James Pullman and Hillel W. Cohen and Sally Lee and Craig J Shapiro and Clemencia Solorzano and Stuart Greenstein and Daniel G Glicklich},
  journal={Journal of the American Society of Nephrology : JASN},
  volume={23 8},
Bisphosphonates may prevent or treat the bone loss promoted by the immunosuppressive regimens used in renal transplantation. Risedronate is a commonly used third-generation amino-bisphosphonate, but little is known about its effects on the bone health of renal transplant recipients. We randomly assigned 42 new living-donor kidney recipients to either 35 mg of risedronate weekly or placebo for 12 months. We obtained bone biopsies at the time of renal transplant and after 12 months of protocol… CONTINUE READING
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