Effect of rifampicin on liver function in man.

@article{Capelle1972EffectOR,
  title={Effect of rifampicin on liver function in man.},
  author={P Capelle and Daniel Dhumeaux and Marina Mora and G. Feldmann and Pascal Berthelot},
  journal={Gut},
  year={1972},
  volume={13 5},
  pages={366-71}
}
Liver function and serum concentrations of rifampicin, a highly cholephilic antibiotic, have been studied after ingestion of a single dose of 600 mg of rifampicin in 12 patients, six of them having a normal liver and six a cirrhotic, and during treatment with 600 mg of rifampicin per day for 17 days in eight patients, four of them having a normal liver and four a cirrhotic. Rifampicin produced competition for the elimination of bilirubin and bromsulphalein by the liver. This competition, which… CONTINUE READING