Effect of resistin on vascular endothelium secretion dysfunction in rats.

  title={Effect of resistin on vascular endothelium secretion dysfunction in rats.},
  author={Yan Li and Yi Wang and Qian Li and Yao Chen and Shu-zhen Sun and Weidong Zhang and Qing Jia},
  journal={Endothelium : journal of endothelial cell research},
  volume={14 4-5},
Resistin, a novel adipokine, was recently suggested to be involved in the development of endothelial dysfunction. However, the mechanisms of how resistin works are still unknown. This study was performed to investigate the relationship between resistin and phosphatidylinositol 3-kinase (PI3K), with the aim of gaining insight to the mechanisms by which resistin induces changes of secretion function of vascular endothelium. This study was conducted on 60 male 4-week-old Sprague-Dawley rats, which… CONTINUE READING
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