Effect of repetitive transcranial magnetic stimulation on serum brain derived neurotrophic factor in drug resistant depressed patients.

@article{Zanardini2006EffectOR,
  title={Effect of repetitive transcranial magnetic stimulation on serum brain derived neurotrophic factor in drug resistant depressed patients.},
  author={R. A. D. Zanardini and Anna Gazzoli and Mariacarla Ventriglia and J. Zu{\~n}iga P{\'e}rez and Stefano Bignotti and Paolo Maria Rossini and Massimo Gennarelli and Luisella Bocchio-Chiavetto},
  journal={Journal of affective disorders},
  year={2006},
  volume={91 1},
  pages={83-6}
}
BACKGROUND Depression has been associated with low brain-derived neurotrophic factor (BDNF) serum levels, while antidepressant drugs appear to mend this alteration. The purpose of this study was to assess BDNF serum levels in drug resistant depressed patients before and after repetitive Transcranial Magnetic Stimulation (rTMS) antidepressant treatment. METHODS BDNF levels were measured in serum of 16 resistant depressed patients using the ELISA technique. RESULTS BDNF baseline levels showed… CONTINUE READING
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