Effect of repeated ingestion of aspartame-sweetened beverage on plasma amino acid, blood methanol, and blood formate concentrations in normal adults.

@article{Stegink1989EffectOR,
  title={Effect of repeated ingestion of aspartame-sweetened beverage on plasma amino acid, blood methanol, and blood formate concentrations in normal adults.},
  author={Lewis D. Stegink and L. J. Jr. Filer and Edward F. Bell and Ekhard E. Ziegler and Thomas R. Tephly},
  journal={Metabolism: clinical and experimental},
  year={1989},
  volume={38 4},
  pages={
          357-63
        }
}
  • Lewis D. Stegink, L. J. Jr. Filer, +2 authors Thomas R. Tephly
  • Published 1989
  • Chemistry, Medicine
  • Metabolism: clinical and experimental
  • Aspartame (APM) is a widely used dipeptide sweetener (L-aspartyl-L-phenylalanine methyl ester). It has been suggested that excessive use of APM might elevate plasma aspartate, phenylalanine, and/or methanol concentrations to levels that are potentially harmful. Six normal young adults ingested eight successive servings of unsweetened and APM-sweetened beverage at one-hour intervals in a balanced crossover design. In one part, the beverage was not sweetened. In the other, each serving of… CONTINUE READING

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