Effect of relA Activation on UV and Antibiotic Sensitivity

Abstract

The stringent response in starvation conditions is a well documented activation of the RelA protein, which synthesizes guanosine 3’, 5’ bisphosphate (ppGpp). Aside from inducing global changes in gene expression, increased cellular ppGpp levels have previously been found to confer resistance to penicillin. We used Escherichia coli strains with relA… (More)

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