Effect of reduced oxygen tension on reactive oxygen species production and activity of antioxidant enzymes in swine granulosa cells.

@article{Basini2004EffectOR,
  title={Effect of reduced oxygen tension on reactive oxygen species production and activity of antioxidant enzymes in swine granulosa cells.},
  author={Giuseppina Basini and Francesca Grasselli and Federico Bianco and Martina Tirelli and Carlo Tamanini},
  journal={BioFactors},
  year={2004},
  volume={20 2},
  pages={61-9}
}
During follicle growth swine granulosa cells are physiologically exposed to a progressive oxygen shortage. It has already been shown that hypoxia stimulates angiogenesis through an increase of VEGF production, however, despite considerable progress in the understanding of the final events induced by cellular hypoxia, the signal transduction pathway remains… CONTINUE READING