Effect of recombinant interferons on hairy cell leukemia progenitors.

@article{Masuda1989EffectOR,
  title={Effect of recombinant interferons on hairy cell leukemia progenitors.},
  author={Michihiko Masuda and Minoko Takanashi and Toshiko Motoji and Kazuo Oshimi and Hideaki Mizoguchi},
  journal={International journal of cell cloning},
  year={1989},
  volume={7 2},
  pages={
          120-8
        }
}
The effects of recombinant interferons (rIFNs) on colony formation by progenitor cells from the peripheral blood of patients with hairy cell leukemia (HCL) were examined. Results showed that both rIFN-alpha and -beta inhibited HCL colony formation in a dose-dependent manner, with the inhibitory effect of rIFN-alpha being similar in degree with that of rIFN-beta. The inhibitory effect of rIFN-gamma, however, was not uniform; of four patients, inhibition was observed in cells from two patients… 
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Interferon-? Stimulates the Survival and Influences the Development of Bipotential Granulocyte-Macrophage Colony-Forming Cells By 0
TLDR
The effects of interferon-y (IFN-y) on a highly enriched population of granulocyte-macrophage colony-forming cells (GM-CFC) were assessed and IFNy stimulated an increase in the number of macrophages present in colonies formed in the presence of IL-3.

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TLDR
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TLDR
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