Effect of recombinant granulocyte/macrophage colony-stimulating factor on human monocyte activity in vitro and following intravenous administration.

@article{Kleinerman1988EffectOR,
  title={Effect of recombinant granulocyte/macrophage colony-stimulating factor on human monocyte activity in vitro and following intravenous administration.},
  author={Eugenie S Kleinerman and Rebecca D. Knowles and Lawrence B. Lachman and Jordan U. Gutterman},
  journal={Cancer research},
  year={1988},
  volume={48 9},
  pages={2604-9}
}
The purpose of these studies was to examine the antitumor properties of blood monocytes from patients undergoing a phase I trial with recombinant granulocyte/macrophage colony-stimulating factor (rGM-CSF). Peripheral blood monocytes from 7 patients receiving various doses of rGM-CSF by continuous infusion were isolated prior to therapy and at various times during the 2-wk infusion. Monocytes/cubic centimeter of blood increased in a dose-dependent fashion in patients receiving rGM-CSF. However… CONTINUE READING

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Human interleukin 1 from leukemia monocytes

L. B. Lachman, Shih, N L-C., D. C. Brown
Methods Enzymol., • 1985
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