Effect of recombinant GM-CSF on the metabolism of cytosine arabinoside in normal and leukemic human bone marrow cells.

@article{Bhalla1988EffectOR,
  title={Effect of recombinant GM-CSF on the metabolism of cytosine arabinoside in normal and leukemic human bone marrow cells.},
  author={K N Bhalla and Martin J. Birkhofer and Zalmen A. Arlin and Steven Grant and Jose Lutzky and Gerard Graham},
  journal={Leukemia},
  year={1988},
  volume={2 12},
  pages={810-3}
}
Human recombinant GM-CSF (rGM-CSF) is under investigation as a growth-protective agent for normal hematopoietic elements in phase I trials of myelosuppressive chemotherapy and in bone marrow transplantation. We determined the effect of rGM-CSF on the metabolism of high dose Ara-C in bone marrow mononuclear cells (BMMCs) from healthy volunteers and patients… CONTINUE READING