Effect of rapid delayed rectifier current on hysteresis in restitution of action potential duration in swine

Abstract

Electrical stability in the heart depends on two important factors; restitution of action potential duration (APD) and memory. Repolarization currents play an important role in determining APD and also affect memory. We determined the effects of blocking the rapid component of the delayed rectifier (IKr) on a quantifiable measure of memory, i.e. hysteresis… (More)
DOI: 10.1109/EMBC.2012.6346021

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