Effect of ranitidine on chloroquine disposition.

  title={Effect of ranitidine on chloroquine disposition.},
  author={Ene I. Ette and A Brown-Awala and E. E. Essien},
  journal={Drug intelligence & clinical pharmacy},
  volume={21 9},
Ten healthy, male volunteers (aged 19-27 yr; weight 62-67 kg) were randomly distributed into control and test groups of five subjects each in a controlled study on the effect of ranitidine on chloroquine disposition. The control group subjects received two tablets of chloroquine sulfate (300-mg base) only. The test group subjects received ranitidine 250 mg hs for four days prior to the administration of chloroquine sulfate and throughout the sample collection period. Blood samples (5 ml) were… CONTINUE READING

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