Effect of ramipril, nifedipine, and moxonidine on glomerular morphology and podocyte structure in experimental renal failure.

@article{Amann1996EffectOR,
  title={Effect of ramipril, nifedipine, and moxonidine on glomerular morphology and podocyte structure in experimental renal failure.},
  author={Kerstin Amann and C G Nichols and J Tornig and Ute I. Schwarz and Martin G. Zeier and Gerhard Mall and Eberhard Ritz},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={1996},
  volume={11 6},
  pages={1003-11}
}
BACKGROUND Experimental renal failure causes structural alterations of the kidney. It is still unresolved how these changes are modified by antihypertensive treatment. Purpose of the study. To examine the effects of different antihypertensive agents (ramipril, nifedipine, moxonidine) mainly on glomerular geometry, cell number, cell morphology, and capillarization, in a subtotal nephrectomy model of renal failure. MATERIAL AND METHODS Sham-operated male SD rats and subtotally nephrectomized… CONTINUE READING

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