Effect of race and genetics on vitamin D metabolism, bone and vascular health

  title={Effect of race and genetics on vitamin D metabolism, bone and vascular health},
  author={B. Freedman and T. Register},
  journal={Nature Reviews Nephrology},
  • B. Freedman, T. Register
  • Published 2012
  • Medicine
  • Nature Reviews Nephrology
  • The pathophysiology of chronic kidney disease–mineral and bone disorder accounts for an inverse relationship between bone mineralization and vascular calcification in progressive nephropathy. Inverse associations between bone mineral density (BMD) and calcified atherosclerotic plaque are also observed in individuals of European and African ancestry without nephropathy, suggesting a mechanistic link between these processes that is independent of kidney disease. Despite lower dietary calcium… CONTINUE READING
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