Effect of quinapril therapy on blood pressure and serotonin change in patients with mild to moderate hypertension.

BACKGROUND Previous studies have shown that serotonin plays an important role in hypertension because of its vasoconstrictive effect, mediated through serotonergic receptors. Angiotensin-II is a potent vasopressor which facilitates the aggregation of platelets, subsequently releases serotonin. Because quinapril is an angiotensin-converting enzyme inhibitor… CONTINUE READING