Effect of quetiapine XR on depressive symptoms and sleep quality compared with lithium in patients with bipolar depression.

@article{Kim2014EffectOQ,
  title={Effect of quetiapine XR on depressive symptoms and sleep quality compared with lithium in patients with bipolar depression.},
  author={Seog Ju Kim and Yu Jin Lee and Yu-Jin G. Lee and Seong-Jin Cho},
  journal={Journal of affective disorders},
  year={2014},
  volume={157},
  pages={
          33-40
        }
}
BACKGROUND Bipolar depression is one of the most serious psychiatric conditions. In addition, sleep disturbance in bipolar disorder is common, and therapeutic agents restoring sleep disturbances in bipolar disorder patients will be clinically beneficial. In the current study, we compared the effect of quetiapine XR with lithium on depressive symptoms and sleep in bipolar depression patients during 8 weeks of trial. METHODS An open-label, randomized comparison of sleep-activity and depressive… CONTINUE READING
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