Effect of pyruvate, octanoate and glucose on leucine degradation in skeletal muscle from fed and fasted chicks.

@article{Wu1988EffectOP,
  title={Effect of pyruvate, octanoate and glucose on leucine degradation in skeletal muscle from fed and fasted chicks.},
  author={Gordon Ying-Qing Wu and Jeffrey R. Thompson},
  journal={The International journal of biochemistry},
  year={1988},
  volume={20 5},
  pages={521-6}
}
1. Pyruvate at 5 mM decreased the rate of leucine oxidative decarboxylation and increased the rate of 2-oxoisocaproate production in extensor digitorum communis (EDC) muscles from both fed and 24-hr fasted chicks. Pyruvate at 5 mM increased the net rate of leucine transamination in EDC muscle from fed chicks and had no effect in EDC muscles from 24-hr fasted chicks. 2. Octanoate at 0.2 and 1 mM markedly increased the rates of net leucine transamination, leucine oxidative decarboxylation and… CONTINUE READING

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