Effect of putrescine on S-adenosylmethionine decarboxylase in a small intestinal crypt cell line.

Abstract

Two key enzymes in polyamine biosynthesis are ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (SAMDC). SAMDC decarboxylates S-adenosylmethionine, which then donates aminopropyl groups for spermidine and spermine synthesis. The purpose of our study was to determine whether putrescine, taken up from medium or synthesized endogenously by… (More)

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@article{Wang1992EffectOP, title={Effect of putrescine on S-adenosylmethionine decarboxylase in a small intestinal crypt cell line.}, author={J Wang and Mary Jane Viar and Shirley A. McCormack and Leonard R. Johnson}, journal={The American journal of physiology}, year={1992}, volume={263 4 Pt 1}, pages={G494-501} }