Effect of psychological stress on salivary interleukin-1beta in psoriasis.

  title={Effect of psychological stress on salivary interleukin-1beta in psoriasis.},
  author={Mario Mastrolonardo and Dario Alicino and Roberto Zefferino and Paolo Pasquini and Angelo Picardi},
  journal={Archives of medical research},
  volume={38 2},
BACKGROUND Psoriasis is a chronic inflammatory skin disease in which several Th1 cytokines such as interleukin-1 beta (IL-beta) have been shown to play a pivotal role. Psychological stress has also been implicated in triggering or exacerbating the disease. METHODS Salivary IL-1beta and cortisol levels of 25 patients with psoriasis were compared with those of 50 age- and sex-matched healthy controls under basal conditions and after a standardized stressful procedure including mental… CONTINUE READING

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