Effect of protocatechuic acid on insulin responsiveness and inflammation in visceral adipose tissue from obese individuals: possible role for PTP1B

@article{Ormazabal2018EffectOP,
  title={Effect of protocatechuic acid on insulin responsiveness and inflammation in visceral adipose tissue from obese individuals: possible role for PTP1B},
  author={Paulina Ormazabal and B Scazzocchio and Rosaria M Var{\`i} and Carmela Santangelo and M D'Archivio and Gianfranco Silecchia and Annunziata Iacovelli and C Giovannini and Roberta Masella},
  journal={International Journal of Obesity},
  year={2018},
  volume={42},
  pages={2012-2021}
}
The occurrence of chronic inflammation in visceral adipose tissue (VAT) in obese subjects precipitates the development of insulin resistance and type 2 diabetes (T2D). Anthocyanins and their main metabolite protocatechuic acid (PCA) have been demonstrated to stimulate insulin signaling in human adipocytes. The aim of this study was to investigate whether PCA is able to modulate insulin responsiveness and inflammation in VAT from obese (OB) and normal weight (NW) subjects. VATs obtained from NW… CONTINUE READING
BETA

Citations

Publications citing this paper.

Effects of astaxanthin supplementation in healthy and obese dogs

  • Veterinary medicine
  • 2019
VIEW 2 EXCERPTS
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 54 REFERENCES

Nuclear factor kappaB signaling in atherogenesis.

  • Arteriosclerosis, thrombosis, and vascular biology
  • 2005
VIEW 13 EXCERPTS
HIGHLY INFLUENTIAL

Protective effects of protocatechuic acid on acute lung injury induced by lipopolysaccharide in mice via p38MAPK and NF-kappaB signal pathways

X Zhang
  • Int Immunopharmacol
  • 2015
VIEW 1 EXCERPT

Similar Papers

Loading similar papers…