Effect of protein dose on serum glucose and insulin response to sugars.

@article{Spiller1987EffectOP,
  title={Effect of protein dose on serum glucose and insulin response to sugars.},
  author={Gene A. Spiller and C. D. Jensen and T. S. Pattison and Christine Chuck and James H. Whittam and James Scala},
  journal={The American journal of clinical nutrition},
  year={1987},
  volume={46 3},
  pages={
          474-80
        }
}
To clarify the effects of protein on insulin and glucose response to sugars, 14 healthy normal-weight males and females were fed test meals containing 0, 15.8, 25.1, 33.6, and 49.9 g protein along with approximately 58 g carbohydrate. Serum samples were obtained at fasting time zero and 15, 30, 60, and 120 min postprandial. Mean areas of the glucose curves above fasting decreased with increasing protein dose. Protein-containing meals produced significantly lower (p less than 0.01) areas than… 
View on PubMed
doi.org
112 Citations
Highly Influential Citations
6
Background Citations
47
Methods Citations
2
Results Citations
4

Figures and Tables from this paper

112 Citations

The effects of fat and protein on glycemic responses in nondiabetic humans vary with waist circumference, fasting plasma insulin, and dietary fiber intake.

It is concluded that, across the range of 0-30 g, protein and fat reduced glycemic responses independently from each other in a linear, dose-dependent fashion, with protein having approximately 3-times the effect of fat.

Prediction of glucose and insulin responses of normal subjects after consuming mixed meals varying in energy, protein, fat, carbohydrate and glycemic index.

It is concluded that both amount and source of carbohydrate determine the glucose and insulin responses of lean, young, nondiabetic subjects after different mixed meals with variable glycemic index.

Glycemic and insulinemic responses to protein supplements.

Insulin sensitivity predicts glycemia after a protein load.

Human and Clinical Nutrition Source and Amount of Carbohydrate Affect PostprandialGlucose and Insulin in Normal Subjects 1

It is concluded that, for individual foods with different glycémieindi ces, both source and amount of carbohydrate influence the postprandial glucose and insulin responses of nondiabetic subjects.

Effects of low doses of casein hydrolysate on post-challenge glucose and insulin levels.

Glycemic response to carbohydrate and the effects of exercise and protein.

Glucagon and insulin responses after ingestion of different amounts of intact and hydrolysed proteins

Insulin and glucagon responses increased with increasing protein load for SPI, SPH, WPI and WPH, but the effect was more pronounced for glucagon, an important parameter for the control of postprandial substrate metabolism.

Postprandial glucose and insulin responses to various tropical fruits of equivalent carbohydrate content in non-insulin-dependent diabetes mellitus.

Insulin and glucose responses after ingestion of different loads and forms of vegetable or animal proteins in protein enriched fruit beverages

...