Effect of prolonged modified fasting in obese persons on in vitro markers of immunity: lymphocyte function and serum effects on normal neutrophils.

@article{Mcmurray1990EffectOP,
  title={Effect of prolonged modified fasting in obese persons on in vitro markers of immunity: lymphocyte function and serum effects on normal neutrophils.},
  author={R W Mcmurray and Robert W. Bradsher and Russell W Steele and N S Pilkington},
  journal={The American journal of the medical sciences},
  year={1990},
  volume={299 6},
  pages={379-85}
}
The effects of nutritional manipulation on immune function have been extensively studied in animals, but few studies have examined dietary restriction in humans. Obese patients enrolled in a protein-sparing, calorically restricted diet were monitored over a 3-month period with in vitro examination of mitogen- and antigen-induced lymphocyte blastogenesis. The sera from these patients were evaluated for effects on neutrophil chemotaxis, phagocytosis and microbial killing. Significant changes in… CONTINUE READING