• Corpus ID: 7985930

Effect of prolonged exposure to 0.5% CO2 on kidney calcification and ultrastructure of lungs.

@article{Schaefer1979EffectOP,
  title={Effect of prolonged exposure to 0.5\% CO2 on kidney calcification and ultrastructure of lungs.},
  author={Karl Ernst Schaefer and William H. J. Douglas and Arthur A. Messier and Michael L. Shea and Paul Alton Gohman},
  journal={Undersea biomedical research},
  year={1979},
  volume={6 Suppl},
  pages={
          S155-61
        }
}
Guinea pigs were exposed for up to 8 weeks to 0.5% CO2, 21% O2, and balance N2. Control groups of the same age were kept simultaneously in environmental chambers on air. A slight increase in PaCO2 and decrease in pH were observed at various periods of exposure to 0.5% CO2. After eight weeks of exposure, an increased kidney calcification, indicated by increased kidney calcium content, was found. Plasma calcium was significantly elevated at this point, apparently because of the release of calcium… 
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