Effect of prolonged bicarbonate administration on plasma potassium in terminal renal failure.

@article{Blumberg1992EffectOP,
  title={Effect of prolonged bicarbonate administration on plasma potassium in terminal renal failure.},
  author={Alfred Blumberg and Prof. P. Weidmann and Paolo Ferrari},
  journal={Kidney international},
  year={1992},
  volume={41 2},
  pages={
          369-74
        }
}
In hemodialysis patients with hyperkalemia, i.v. sodium bicarbonate has recently been found to be ineffective in lowering plasma potassium within one hour. In the present study the effect of a prolonged bicarbonate infusion on plasma potassium was investigated. Twelve patients with terminal renal failure who were on hemodialysis were infused i.v. with 8.4% sodium bicarbonate (4 mmol/min) for one hour and with 1.4% (0.5 mmol/min) for five hours (total amount 390 mmol). Plasma bicarbonate rose… 
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