Effect of probiotic mix (Bifidobacterium bifidum, Bifidobacterium lactis, Lactobacillus acidophilus) in the primary prevention of eczema: a double‐blind, randomized, placebo‐controlled trial

@article{Kim2010EffectOP,
  title={Effect of probiotic mix (Bifidobacterium bifidum, Bifidobacterium lactis, Lactobacillus acidophilus) in the primary prevention of eczema: a double‐blind, randomized, placebo‐controlled trial},
  author={Ji Yeun Kim and Jung Hyun Kwon and So Hyun Ahn and Sang Il Lee and Youngshin Han and Young Ok Choi and Soo Young Lee and Kangmo Ahn and Geun Eog Ji},
  journal={Pediatric Allergy and Immunology},
  year={2010},
  volume={21}
}
Controversy exists regarding the preventive effect of probiotics on the development of eczema or atopic dermatitis. [] Key Method In a randomized, double-blind, placebo-controlled trial, 112 pregnant women with a family history of allergic diseases received a once-daily supplement, either a mixture of Bifidobacterium bifidum BGN4, B. lactis AD011, and Lactobacillus acidophilus AD031, or placebo, starting at 4-8 wks before delivery and continuing until 6 months after delivery.
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245 Citations
Highly Influential Citations
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Background Citations
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Methods Citations
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Results Citations
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245 Citations

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TLDR
The mixed strain of Lactobacillus and Bifidobacterium mixed strain can effectively reduce the incidence of eczema in infants under three years old, and further research is needed to fully understand the exact mechanism of their effect on infant Eczema.
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Lactobacillus GG treatment during pregnancy for the prevention of eczema: a randomized controlled trial.
Multistrain Probiotics: The Present Forward the Future
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TLDR
Oral administration of the probiotic NCC2818 mitigates immune parameters and allergic symptoms during seasonal exposure and promising results warrant that B. lactis N CC2818 be investigated further in large-scale trials for management of respiratory allergy.
Prebiotics, Probiotics, and Synbiotics: A Bifidobacterial View
Probiotics in neonatology
TLDR
The evidence for probiotic supplementation in neonatology is reviewed, with a focus on preterm infants, to report the effects of probiotics on important clinical outcomes in neonates.
A protective effect of Lactobacillus rhamnosus HN001 against eczema in the first 2 years of life persists to age 4 years
  • K. Wickens, P. Black, +5 authors J. Crane
  • Medicine
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
  • 2012
TLDR
In a high risk birth cohort, maternal supplementation from 35 weeks gestation until 6 months if breastfeeding and infant supplementation until 2 years with Lactobacillus rhamnosus HN001 (HN001) (6 × 109 cfu/day) halved the cumulative prevalence of eczema by age 2 years.
Gut microbiota profile in children affected by atopic dermatitis and evaluation of intestinal persistence of a probiotic mixture
TLDR
Results show an alteration in AD microbiota composition with the depletion or absence of some species, opening the way to future probiotic intervention studies.
Probiotics for the treatment of bacterial vaginosis.
BACKGROUND The dominance of lactobacilli in healthy vaginal microbiota and its depletion in bacterial vaginosis (BV) has given rise to the concept of oral or vaginal instillation of probiotic…
Effect of nutrient supplementation on atopic dermatitis in children: a systematic review of probiotics, prebiotics, formula, and fatty acids.
TLDR
Certain types of nutrient supplementation are beneficial in preventing AD development and reducing its severity and future research elucidating the mechanisms underlying the actions of nutritional supplementation on AD is necessary.
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References

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TLDR
Results indicate that L. acidophilus AD031 and B. lactis AD011 might be useful for the prevention of allergy and suppressed production of the OVA-specific IgE, IgG1, and IgA.
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TLDR
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