Effect of prior cancer on outcomes in advanced lung cancer: implications for clinical trial eligibility and accrual.

@article{Laccetti2015EffectOP,
  title={Effect of prior cancer on outcomes in advanced lung cancer: implications for clinical trial eligibility and accrual.},
  author={Andrew L Laccetti and Sandi L. Pruitt and Lei Xuan and Ethan A. Halm and David E. Gerber},
  journal={Journal of the National Cancer Institute},
  year={2015},
  volume={107 4}
}
BACKGROUND Prior cancer is a common exclusion criterion in lung cancer trials. This practice reflects concerns that prior cancer may affect trial conduct or outcomes. However, the impact of prior cancer on survival in lung cancer is not known. METHODS We identified patients older than age 65 years with stage IV lung cancer diagnosed between 1992 and 2009 in the Surveillance, Epidemiology, and End Results-Medicare linked registry. Prior cancer was characterized by type, stage, and timing. All… CONTINUE READING
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