Effect of praziquantel on serum glucose and insulin levels in normal and hyperglycemic rats.

@article{Elkashef1996EffectOP,
  title={Effect of praziquantel on serum glucose and insulin levels in normal and hyperglycemic rats.},
  author={Hassan A. El-kashef and Hatem A Salem and Shehta Abd-Allah Said and Mohamed M. A. Elmazar},
  journal={Arzneimittel-Forschung},
  year={1996},
  volume={46 4},
  pages={433-5}
}
The effects of praziquantel (CAS 55268-74-1) on serum glucose and insulin levels in normoglycemic and hyperglycemic rats were studied. Also the combined effect of praziquantel and glibenclamide (CAS 10238-21-8) on oral glucose tolerance in rats was investigated. Praziquantel, given orally in a dose of 250 mg/kg, significantly increased serum glucose level in hyperglycemic rats without changing serum insulin level. After oral glucose load, praziquantel produced a significant increase in serum… CONTINUE READING