Effect of potassium depletion on chloride transport in the loop of Henle in the rat.

@article{Luke1985EffectOP,
  title={Effect of potassium depletion on chloride transport in the loop of Henle in the rat.},
  author={Robert G. Luke and B B Booker and John H. Galla},
  journal={The American journal of physiology},
  year={1985},
  volume={248 5 Pt 2},
  pages={F682-7}
}
Microperfusion of the superficial loop segment (latest proximal to earliest distal tubule) was performed in potassium-depleted and control rats. Potassium depletion was confirmed by analysis of muscle content (control 45 +/- 2, potassium depletion 33.5 +/- 0.9 meq/100 g dry solids). During perfusion at 20 nl/min net chloride absorption was decreased (66 +/- 3 vs. 77 +/- 2%, P less than 0.01) and early distal chloride concentration increased (70 +/- 5 vs. 50 +/- 4 meq/liter, P less than 0.01) in… CONTINUE READING