Effect of potassium citrate supplementation or increased fruit and vegetable intake on bone metabolism in healthy postmenopausal women: a randomized controlled trial.

@article{Macdonald2008EffectOP,
  title={Effect of potassium citrate supplementation or increased fruit and vegetable intake on bone metabolism in healthy postmenopausal women: a randomized controlled trial.},
  author={Helen M. Macdonald and Alison J. Black and Lorna Sharman Aucott and G. Andrew Duthie and Susan J. Duthie and Rena Sandison and Antonia C. Hardcastle and Susan A Lanham New and W. D. Fraser and David M. Reid},
  journal={The American journal of clinical nutrition},
  year={2008},
  volume={88 2},
  pages={465-74}
}
BACKGROUND Alkali provision may explain why fruit and vegetables benefit bone health. OBJECTIVE We aimed to determine the effects of alkali-providing potassium citrate (double-blind) and fruit and vegetable intake (single-blind) on bone turnover over 2 y. DESIGN We conducted a randomized placebo-controlled trial in 276 postmenopausal women (aged 55-65 y). Women were randomly assigned to 4 groups: high-dose potassium citrate (55.5 mEq/d), low-dose potassium citrate (18.5 mEq/d), placebo, and… CONTINUE READING
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