[Effect of postaurical subcutaneously injection of triamcinolone acetonide for subjective tinnitus].

Abstract

OBJECTIVE To determine whether postaurical subcutaneous injection of triamcinolone acetonide is effective for subjective tinnitus refractory to medical treatment. METHODS A total of 100 adult patients with subjective tinnitus of cochlear origin were randomly assigned to receive postaurical subcutaneous.Injection of either triamcinolone acetonide (n = 50) or saline solution (n = 50). The treatment protocol comprised 5 injections, one per week for 5 weeks.Improvement was measured by tinnitus severity evaluation index evaluation scale, at baseline and one week after the last injection. The follow-up period was 6 months. RESULTS No significant difference existed between two groups regarding age, gender, pure tone average, pretreatment tinnitus intensity, tinnitus duration or hearing loss level tinnitus duration (P = 0.316,0.685,0.839,0.682 and 0.881 respectively).No significant post-treatment changes in the tinnitus severity index (experimental group = 52%, control group = 44%) were observed in either group (P = 0.724). The most frequently encountered side effect was pain during injection. CONCLUSION The postaurical subcutaneous injection of triamcinolone acetonide has no obvious benefit compared with placebo for subjective tinnitus of cochlear origin refractory to medical treatment.

Cite this paper

@article{Diao2013EffectOP, title={[Effect of postaurical subcutaneously injection of triamcinolone acetonide for subjective tinnitus].}, author={Ming-fang Diao and Jianjun Sun and Fang-jie Tian and Shuang Xu and Zhong-hong Jia and Yang Liu and Dong-lan Chen}, journal={Zhonghua yi xue za zhi}, year={2013}, volume={93 42}, pages={3384-7} }