Effect of polyclonal and monoclonal HLA-DR xenoantibodies on xenogeneic mixed lymphocyte reactions


Human lymphoid cells can stimulate xenogeneic lymphoid cells in mixed lymphocyte reactions (MLRs) (Widmer and Bach 1972, Russo et al. 1980). This reaction has been suggested to be mediated by histocompatibility antigens and to reflect cross-reactivity between histocompatibility antigens from different animal species. Blocking of MLRs by specific antibodies… (More)
DOI: 10.1007/BF01567808


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