Effect of pirfenidone on mortality: pooled analyses and meta-analyses of clinical trials in idiopathic pulmonary fibrosis.

@article{Nathan2017EffectOP,
  title={Effect of pirfenidone on mortality: pooled analyses and meta-analyses of clinical trials in idiopathic pulmonary fibrosis.},
  author={Steven Nathan and Carlo Albera and Williamson Z. Bradford and Ulrich Costabel and Ian N Glaspole and Marilyn K. Glassberg and David R Kardatzke and Monica Daigl and Klaus-Uwe Kirchgaessler and Lisa H. Lancaster and David J. Lederer and Carlos A C Pereira and Jeffrey J. Swigris and Dominique Valeyre and Paul W. Noble},
  journal={The Lancet. Respiratory medicine},
  year={2017},
  volume={5 1},
  pages={33-41}
}
BACKGROUND In clinical trials of idiopathic pulmonary fibrosis, rates of all-cause mortality are low. Thus prospective mortality trials are logistically very challenging, justifying the use of pooled analyses or meta-analyses. We did pooled analyses and meta-analyses of clinical trials of pirfenidone versus placebo to determine the effect of pirfenidone on… CONTINUE READING