Effect of piracetam on extrapyramidal side effects induced by neuroleptic drugs.

  title={Effect of piracetam on extrapyramidal side effects induced by neuroleptic drugs.},
  author={J. Kabe{\vs} and J. Sikora and J. Pisvejc and L. Hanzl{\'i}cek and V. Skondia},
  journal={International pharmacopsychiatry},
  volume={17 3},
In a double-blind crossover placebo controlled trial the effectivity of piracetam in neuroleptic-induced extrapyramidal side effects was confirmed. 40 psychotic patients treated with neuroleptics in an average daily dose equal to 600 mg of chlorpromazine were included in this study. Akathisia, tremor, muscle rigidity and dyskinesia were evaluated on a 4-point scale. The patients were randomly divided into two subgroups--40 g of piracetam or placebo from identic ampoules were given i.v. with a… Expand
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A rating scale for acute drug-induced akathisia: development, reliability, and validity
  • P. Sachdev
  • Psychology, Medicine
  • Biological Psychiatry
  • 1994
This paper describes the process of developing a new rating scale for acute neuroleptic-induced akathisia, and a preliminary examination of its construct validity was performed by calculating the correlations with the ratings on the analogue and global scales. Expand