Effect of pinealectomy and melatonin on vasopressin-potentiated passive avoidance in rats.

@article{Juszczak1996EffectOP,
  title={Effect of pinealectomy and melatonin on vasopressin-potentiated passive avoidance in rats.},
  author={Marlena Juszczak and Jacek Drobnik and Jan W. Guzek and Helmut Schwarzberg},
  journal={Journal of physiology and pharmacology : an official journal of the Polish Physiological Society},
  year={1996},
  volume={47 4},
  pages={621-7}
}
The pineal indoleamine, melatonin, and the hypothalamic neuropeptide, vasopressin, facilitate passive avoidance behaviour in rats. The similarity of the effects suggest that interaction might occur between the two substances. Therefore, the effect of intraperitoneally applied vasopressin and/or melatonin on one-trial learning passive avoidance behaviour was studied in pinealectomized rats. Intraperitoneal treatment with 500 ng vasopressin 1 hr before the retention test increased passive… CONTINUE READING