Effect of piceatannol in human monocyte-derived dendritic cells in vitro.

@article{Takei2005EffectOP,
  title={Effect of piceatannol in human monocyte-derived dendritic cells in vitro.},
  author={Masao Takei and Akemi Umeyama and Shigenobu Arihara and Hitoshi Matsumoto},
  journal={Journal of pharmaceutical sciences},
  year={2005},
  volume={94 5},
  pages={974-82}
}
Piceatannol is an anti-inflammatory, immunomodulatory, and antiproliferative stilbene that has been shown to interfere with the cytokine signaling pathway. Dendritic cells (DCs) play a pivotal in the initiation of T-cell-mediated immune responses, making them an attractive cellular adjuvant for use in cancer vaccines. This study investigated the effect of piceatannol on the phenotypic and functional maturation of human monocyte-derived DCs in vitro. Human monocytes were cultured with GM-CSF and… CONTINUE READING