Effect of physical exercise on one-sample antipyrine clearance.


Moderate physical exercise for a few hours is not expected to reduce the hepatic elimination of drugs exhibiting capacity-limited metabolism (low-clearance drugs such as antipyrine). However, previous studies have shown that antipyrine half-life, measured by the multiple-sampling technique, is increased by exercise. A simplified one-sample procedure for… (More)


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@article{Fabbri1991EffectOP, title={Effect of physical exercise on one-sample antipyrine clearance.}, author={Andrea Fabbri and G. Bianchi and Marco Zoli and Elisa Marchi and Giulio Marchesini}, journal={The Italian journal of gastroenterology}, year={1991}, volume={23 2}, pages={74-6} }