Effect of phycocyanin in zymosan-induced arthritis in mice—phycocyanin as an antiarthritic compound

@inproceedings{Remirez1999EffectOP,
  title={Effect of phycocyanin in zymosan-induced arthritis in mice—phycocyanin as an antiarthritic compound},
  author={Diadelis Remirez and Arturo Gonz{\'a}lez and Norma Merino and Roc{\'i}o Gonz{\'a}lez and Odelsa Ancheta and Cheyla Romay and Sandra Rodr{\'i}guez},
  year={1999}
}
The antiinflammatory effect of a phycocyanin extract was studied in zymosan-induced arthritis model in mice. Four days after the intraarticular injection of zymosan, (15 mg/ml), phycocyanin (25, 50, and 100 mg/kg p.o) was administered to animals for 8 days. The mice were then killed and the synovial fluid measured for β-glucuronidase. Each knee joint was totally removed for histopathological and ultrastructural studies. Phycocyanin significantly reduced the levels of β-glucuronidase that had… CONTINUE READING

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