Effect of phenylephrine on hemodynamics and splenic dimensions in horses.

  title={Effect of phenylephrine on hemodynamics and splenic dimensions in horses.},
  author={Joanne Hardy and Richard M Bednarski and David S. Biller},
  journal={American journal of veterinary research},
  volume={55 11},
Pharmacologically induced splenic contraction might be useful during certain medical or surgical procedures in horses. The effects of phenylephrine, an alpha 1-adrenergic receptor agonist, on hemodynamic function and splenic dimensions were examined in 6 healthy adult horses. Phenylephrine infusion (1, 3, or 6 micrograms/kg of body weight/min for 15 minutes) resulted in a dose-related increase in mean pulmonary artery pressure; right atrial pressure; systolic, mean, and diastolic arterial… CONTINUE READING

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