• Medicine, Biology
  • Published in
    American journal of…
    1993

Effect of phenylbutazone and repeated endotoxin administration on hemostasis in neonatal calves.

@article{Semrad1993EffectOP,
  title={Effect of phenylbutazone and repeated endotoxin administration on hemostasis in neonatal calves.},
  author={Susan D. Semrad and Ralf Dubielzig},
  journal={American journal of veterinary research},
  year={1993},
  volume={54 8},
  pages={
          1339-46
        }
}
Twenty newborn Holstein calves were allotted at random to 4 groups: group A received 0.9% sterile saline solution; group B received phenylbutazone (5 mg/kg of body weight, IV) and 0.9% sterile saline solution; group C received progressively increasing doses of endotoxin (0.1 to 15 micrograms/kg); and group D received phenylbutazone and endotoxin similarly as did calves of groups B and C, respectively. Phenylbutazone was given once daily and saline solution or endotoxin were given every 8 hours… CONTINUE READING