Effect of phenylalanine on protein synthesis in the developing rat brain.

@article{Agrawal1970EffectOP,
  title={Effect of phenylalanine on protein synthesis in the developing rat brain.},
  author={Harish C. Agrawal and A H Bone and Alan N. Davison},
  journal={The Biochemical journal},
  year={1970},
  volume={117 2},
  pages={325-31}
}
1. Inhibition of the rate of incorporation of [(35)S]methionine into protein by phenylalanine was more effective in 18-day-old than in 8-day-old or adult rat brain. 2. Among the subcellular fractions incorporation of [(35)S]methionine into myelin proteins was most inhibited in 18-day-old rat brain. 3. Transport of [(35)S]methionine and [(14)C]leucine into the brain acid-soluble pool was significantly decreased in 18-day-old rats by phenylalanine (2mg/g body wt.). The decrease of the two amino… CONTINUE READING

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