Effect of perinatal asphyxia on tuberomammillary nucleus neuronal density and object recognition memory: A possible role for histamine?

@article{FloresBalter2016EffectOP,
  title={Effect of perinatal asphyxia on tuberomammillary nucleus neuronal density and object recognition memory: A possible role for histamine?},
  author={Gabriela Flores-Balter and H{\'e}ctor Cordova-Jadue and Alessandra Chiti-Morales and Carolyne Lespay and Jos{\'e} L Vald{\'e}s},
  journal={Behavioural Brain Research},
  year={2016},
  volume={313},
  pages={226-232}
}
Perinatal asphyxia (PA) is associated with long-term neuronal damage and cognitive deficits in adulthood, such as learning and memory disabilities. After PA, specific brain regions are compromised, including neocortex, hippocampus, basal ganglia, and ascending neuromodulatory pathways, such as dopamine system, explaining some of the cognitive disabilities. We hypothesize that other neuromodulatory systems, such as histamine system from the tuberomammillary nucleus (TMN), which widely project to… CONTINUE READING
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