Effect of pentoxiphylline on oxygen transport during hypothermia.

  title={Effect of pentoxiphylline on oxygen transport during hypothermia.},
  author={Marc Hershenson and James A Schena and Paul A Lozano and Michael J. Jacobson and Robert K Crone},
  journal={Journal of applied physiology},
  volume={66 1},
At least two investigators have demonstrated a reduction in O2 extraction during induced hypothermia (Cain and Bradley, J. Appl. Physiol. 55: 1713-1717, 1983; Schumacker et al., J. Appl. Physiol. 63: 1246-1252, 1987). We hypothesized that administration of pentoxiphylline (PTX), a theobromine that lowers blood viscosity and has vasodilator effects, would… CONTINUE READING