Effect of particle size on oral absorption of carvedilol nanosuspensions: in vitro and in vivo evaluation

Abstract

The purpose of this work was to explore the particle size reduction effect of carvedilol on dissolution and absorption. Three suspensions containing different sized particles were prepared by antisolvent precipitation method or in combination with an ultrasonication process. The suspensions were characterized for particle size, surface morphology, and… (More)
DOI: 10.2147/IJN.S87143

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