Effect of partial liquid ventilation on pulmonary vascular permeability and edema after experimental acute lung injury.

@article{Lange2000EffectOP,
  title={Effect of partial liquid ventilation on pulmonary vascular permeability and edema after experimental acute lung injury.},
  author={Neale R Lange and James K Kozlowski and Ren{\'e} Gust and Steve D. Shapiro and Daniel P. Schuster},
  journal={American journal of respiratory and critical care medicine},
  year={2000},
  volume={162 1},
  pages={271-7}
}
We evaluated the effects of partial liquid ventilation (PLV) with two different dosages of the perfluorocarbon LiquiVent (perflubron) on pulmonary vascular permeability and edema formation after oleic acid (OA)-induced acute lung injury in dogs. We used imaging with positron emission tomography to measure fractional pulmonary blood flow, lung water concentration (LWC), and the pulmonary transcapillary escape rate (PTCER) of (68)Ga-labeled transferrin at 5 and 21 h after lung injury in five dogs… CONTINUE READING