Effect of papulacandin B on glucan synthesis in Paracoccidioides brasiliensis.

@article{Dvila1986EffectOP,
  title={Effect of papulacandin B on glucan synthesis in Paracoccidioides brasiliensis.},
  author={T D{\'a}vila and Gioconda San-Blas and Felipe San-Blas},
  journal={Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology},
  year={1986},
  volume={24 3},
  pages={193-202}
}
Papulacandin B, an inhibitor of beta-glucan synthesis in some fungi, was tested on both morphological phases of Paracoccidioides brasiliensis. In vivo, the antibiotic did not affect yeast morphology or growth but it inhibited mycelial growth and yeast----mycelium transformation. Increase of alpha-glucan and decrease of beta-glucan synthesis was also… CONTINUE READING