Effect of pH on theophylline transfer across the everted rat jejunum.

@article{Perry1984EffectOP,
  title={Effect of pH on theophylline transfer across the everted rat jejunum.},
  author={Dennis F. Perry and Philip D. Walson and James Blanchard},
  journal={Journal of pharmaceutical sciences},
  year={1984},
  volume={73 3},
  pages={320-5}
}
The effect of pH on the cumulative transfer of theophylline across the everted rat jejunum in vitro was investigated. Intestinal integrity was assessed by light and scanning electron microscopy, while the biochemical viability of the intestine was evaluated using glucose transfer measurements. The initial (0-30 min) clearance of theophylline was directly… CONTINUE READING