Effect of pH changes in cerebrospinal fluid specimens on bacterial survival and antigen test results.

@article{Cunniffe1996EffectOP,
  title={Effect of pH changes in cerebrospinal fluid specimens on bacterial survival and antigen test results.},
  author={John Cunniffe and S Whitby-Strevens and Mark H. Wilcox},
  journal={Journal of clinical pathology},
  year={1996},
  volume={49 3},
  pages={249-53}
}
AIMS To determine the effect of pH changes occurring in cerebrospinal fluid (CSF) after sampling on the viability of meningitis causing bacteria, and on the performance of agglutination assays used for the rapid detection of bacterial antigens. METHODS The pH of CSF collected via lumbar puncture was measured by various methods, and the effects of the following different incubation conditions on subsequent changes were determined: air at 4 degrees C; air at room temperature (22 degrees C); air… CONTINUE READING

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