Effect of pH and comedication on gastrointestinal absorption of posaconazole: monitoring of intraluminal and plasma drug concentrations.

Abstract

BACKGROUND AND OBJECTIVE Posaconazole (Noxafil®) is an extended-spectrum triazole antifungal agent for prevention and treatment of invasive fungal infections. An inadequate dietary intake and abnormal gastric pH levels are common in critically ill patients receiving antifungal treatment with posaconazole, resulting in unpredictable bioavailability and sub… (More)
DOI: 10.2165/11592630-000000000-00000

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.